Includes bibliographical references and index
|Statement||Lawrence B. Shultz, editor|
|Contributions||Shultz, Lawrence B|
|LC Classifications||QH671 .C385 2007|
|The Physical Object|
|Pagination||xi, 211 p. :|
|Number of Pages||211|
|LC Control Number||2006036810|
Apoptosis provides a current and comprehensive collection of methods for the study of cell death. Using a diverse range of technical approaches and model systems, the chapters in this volume cover topics from the cellular and organismal to the molecular and Edition: 1. Click on the title to browse this book. A million cells in our bodies die every second—they commit suicide by activating a process called apoptosis or other forms of programmed cell death. These mechanisms are essential for survival of the body as a whole and play critical roles in various developmental . The clearest distinction between necrosis and apoptosis is that apoptosis is an orderly process designed to remove unwanted cells; it can also be triggered by damage to the cell. Necrosis is a disordered process.
Apoptosis can be defined as a complex developmental processes and ongoing homeostasis occurs in all tissues and organ systems. Morphologically, apoptosis can be described as cell shrinkage. Apoptosis can be triggered by various stimuli from outside or inside the cell, e.g. by ligation of cell surface receptors, by DNA damage as a cause of defects in DNA repair mechanisms, treatment with. CHAPTER 11 APOPTOSIS Williams Hematology CHAPTER 11 APOPTOSIS ROBERTA A. GOTTLIEB Features of Programmed Cell Death Mitochondrial Alterations Caspase Activation Nuclear Alterations Endogenous Prevention of Apoptosis Apoptosis in Human Disease Insufficient Apoptosis Excessive Apoptosis Chapter References Apoptosis is a physiologic form of cell death that has . This book, the product of a number of contributing authors, aims to describe the basic methods for studying apoptosis. Each method is described clearly Cited by: 1.
But there are a number of reasons I wanted to write a book about this field, cell death and survival, and then wanted to revise it in a second edition. This is a free sample of content from Cell Death: Apoptosis and Other Means to an End, Second Edition. Click here for more information on how to b uy the b ook. The term apoptosis (a-po-toe-sis) was first used in a now-classic paper by Kerr, Wyllie, and Currie in to describe a morphologically distinct form of cell death, although certain components of the apoptosis concept had been explicitly described many years previously (Kerr et al., ; Paweletz, ; Kerr, ).Our understanding of the mechanisms involved in the process of apoptosis Cited by: The historical development of the cell death concept is reviewed, with special attention to the origin of the terms necrosis, coagulation necrosis, autolysis, physiological cell death, programmed cell death, chromatolysis (the first name of apoptosis in ), karyorhexis, karyolysis, and cell suicide, of which there are three forms: by lysosomes, by free radicals, and by a genetic mechanism (apoptosis).Cited by: In Medical Cell Biology (Third Edition), SUMMARY. Apoptosis is a morphologically and biochemically distinct form of programmed cell death that plays an essential role during embryologic development, after birth, and during adulthood. However, deregulation of apoptosis is involved in the pathogenesis of a variety of human diseases. Since the late s, the core components of the.